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Skyrizi (Risankizumab) – Targeted Biologic Treatment for Moderate to Severe Psoriasis

What is Skyrizi (Risankizumab)?

Skyrizi, the brand name for risankizumab, is a prescription biologic medication specifically designed to treat moderate to severe plaque psoriasis in adults. As a selective interleukin-23 (IL-23) inhibitor, Skyrizi works by targeting a key immune pathway responsible for the inflammation and skin cell buildup that characterize psoriasis.

This targeted action helps reduce skin plaques, itching, and redness, providing long-lasting relief and improved skin health.

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How Does Skyrizi Work?

Skyrizi works by selectively blocking interleukin-23 (IL-23), a protein that plays a critical role in driving the immune response involved in psoriasis. By inhibiting IL-23, Skyrizi calms inflammation and prevents the rapid growth of skin cells, which leads to the hallmark thick, scaly plaques of psoriasis.

Thanks to this precise targeting, Skyrizi offers effective symptom control with fewer side effects compared to broader immunosuppressants.

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What Conditions is Skyrizi Used For?

Skyrizi is FDA-approved to treat:

• Moderate to severe plaque psoriasis in adults

• Ongoing clinical trials are exploring its use in psoriatic arthritis and other inflammatory conditions.

If you suffer from persistent, stubborn plaques or itching despite conventional therapies, Skyrizi may be a highly effective treatment option.

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Benefits of Skyrizi (Risankizumab)

Choosing Skyrizi offers multiple advantages:

• ✅ Highly effective at clearing skin plaques

• ✅ Provides long-lasting relief with dosing every 12 weeks after initial doses

• ✅ Targets IL-23 selectively, minimizing broad immune suppression

• ✅ Improves quality of life by reducing itching, scaling, and redness

• ✅ Generally well tolerated with a favorable safety profile

Many patients experience significant improvement within weeks, with continued benefits over time.

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How is Skyrizi Administered?

Skyrizi is administered as a subcutaneous injection using a pre-filled syringe or auto-injector. The dosing schedule typically involves:

• Two starter doses given at week 0 and week 4

• Followed by a maintenance dose every 12 weeks

This infrequent dosing makes Skyrizi a convenient choice for long-term management.

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Possible Side Effects of Skyrizi

While Skyrizi is generally well tolerated, some patients may experience side effects.

Common Side Effects Include:

• Upper respiratory infections (like sinus infections)

• Fatigue

• Injection site reactions (redness, pain, swelling)

• Headache

Rare but Serious Side Effects:

• Allergic reactions

• Increased risk of infections due to immune modulation

⚠️ Always discuss any new or worsening symptoms with your healthcare provider promptly.

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Who Should Not Take Skyrizi?

Skyrizi may not be suitable if you:

• Have an active infection

• Are allergic to risankizumab or any ingredients in Skyrizi

• Are pregnant or breastfeeding (consult your doctor)

Your healthcare professional will assess your medical history and monitor your health during treatment.

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Frequently Asked Questions About Skyrizi

How soon does Skyrizi start working?

Many patients notice improvements within 4 to 16 weeks of starting treatment.

Is Skyrizi better than other psoriasis treatments?

Skyrizi’s selective IL-23 inhibition offers a targeted approach with fewer doses and potentially fewer side effects compared to some other biologics.

Can I use Skyrizi long term?

Yes, Skyrizi is approved for long-term use, with ongoing monitoring by your healthcare provider.

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Buy Skyrizi (Risankizumab) – Prescription Required

Skyrizi is a prescription-only medication and must be administered under the guidance of a qualified healthcare provider. It is available through:

• Specialty pharmacies

• Dermatology clinics

• Authorized healthcare providers

⚠️ Always ensure you source Skyrizi through licensed and reputable channels to guarantee safety and effectiveness.

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Conclusion: Skyrizi – Effective and Convenient Psoriasis Treatment

For adults struggling with moderate to severe plaque psoriasis, Skyrizi (risankizumab) offers a highly effective, convenient, and well-tolerated treatment option. With its targeted action against IL-23 and infrequent dosing schedule, Skyrizi helps many patients regain clearer skin and improved confidence.

✅ Talk to your dermatologist today to see if Skyrizi is right for your psoriasis management plan.